The causes can be:
Biological: Systemic diseases like hyperthyroidism, can lead to premature ejaculation.
Neurobiological: Brain chemistry can result in rapid ejaculation. In particular, irregularities with the neurotransmitter serotonin.
Genetic: Some patient’s bodies may simply be more sensitive to sexual stimulation.
There are also potential psychological causes for premature ejaculation. Relationship issues, depression, anxiety, or low self-esteem can interfere with your sexual performance.